See it in 3D
Ingredient Atlas · Vitamin A

RetinolThe slow, steady smoother

Retinol speeds up cell turnover and nudges skin to make more collagen. It works, but it takes months and needs a gentle start.

Studied strength0.4%
WhenNight only
Start with2–3 nights a week
ResultsMonths, not weeks
Drag to spin · Hydrogens hidden
C20H30O286.45 g/mol · PubChem CID 445354
CarbonOxygen
?

Make this page about your skin

Set up your skin profile in the Skin Lab and this page will show what retinol means for you.

Build my skin

What it does

How strong the evidence is for each job. More dots means more and better studies.

Softens fine lines

In a 24-week study on aged skin, 0.4% retinol reduced fine wrinkles compared with a plain lotion.

Limited

Builds collagen

Biopsies in the same study showed more procollagen and glycosaminoglycans, which help skin hold water.

Limited

Expect an adjustment phase

Dryness, flaking and redness are common at first. Starting slowly gives skin time to adapt.

Common side effect

Where it works in your skin

Simplified, but true to how the research explains it.

Surface filmBarrierLiving epidermisDermis

Step by step

  1. Skin converts retinol into its active form, retinoic acid.
  2. That signals cells to renew faster and fibroblasts to make more collagen.
  3. Over months, fine lines soften and texture evens out.
Try it in the 3D Skin Lab

Which strength?

Products commonly range from about 0.1% to 1%. Start low, especially if your skin is dry or sensitive.

What to pair it with

Go easy

Acids on the same night

Glycolic or other exfoliating acids plus retinol often irritate. Alternate nights.

Vitamin C at the same time

Use vitamin C in the morning and retinol at night.

Pregnancy

Doctors generally advise avoiding retinoids during pregnancy. Ask yours first.

How to use it

  1. Night only

    Cleanse and let your skin dry fully.

  2. A pea-sized amount

    Enough for the whole face. Avoid the eye corners and lips.

  3. Moisturize

    Follow with moisturizer, or apply moisturizer first if you’re sensitive.

  4. SPF every morning

    Protect the fresh skin retinol reveals.

Questions people ask

Why is my skin peeling?

Dryness and flaking are common in the first weeks. Use it less often, add a ceramide moisturizer, and build up slowly.

Can I use retinol and vitamin C?

Yes, at different times. Vitamin C in the morning, retinol at night.

How is retinol different from tretinoin?

Tretinoin is prescription retinoic acid. Retinol has to be converted by your skin first, so it’s gentler and slower.

Can I use retinol while pregnant?

Doctors generally advise avoiding retinoids during pregnancy or while trying to conceive. Ask your doctor about alternatives.

Product picks are coming soon. We'll list retinol products by skin type and price, with clear notes on any affiliate links.

Explore the Skin Lab

Sources

  1. Kafi R, et al. Improvement of naturally aged skin with vitamin A (retinol). Arch Dermatol. 2007;143(5):606–612. PubMed
  2. EurekAlert summary of the study (University of Michigan). Summary
Draft: pending review by a dermatologist or cosmetic chemistLast updated 6 Nov 2026